Migraine is a common disorder affecting 17% of all women and 8% of all men during the most productive years of their lives. In Europe alone it is estimated that migraine causes an economic loss of over Euro 18 billion a year!
Present medication available is not universally effective and other treatment modalities are needed.
The pathophysiology of migraine include reduction in GLUT1, glucose metabolism, mitochondrial function and ATP production with increase in oxidants (ROS), cortical excitability and cortical spreading depression. Reduced G.I. health and abnormal microbiota are seen.
All of these can be remedied by ketones especially BHB (Betahydroxy butyrate)